Variceal bleeding prophylaxis

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Patients with variceal upper gastrointestinal haemorrhage are at risk of Gram negative sepsis.

Recommended duration: 3 days

Antimicrobial recommendation

Co-amoxiclav 1.2g every 8 hours IV

Penicillin allergy

Co-trimoxazole 960mg every 12 hours IV

Once oral route is available IV to oral switch using the same agent