If CRB65=0
Amoxicillin
500mg 3 x daily
5 days
Alternative treatment
If CRB65=0
Doxycycline
(not suitable for those under 12 years)
200mg on Day 1
then 100mg daily
5 days
OR
If CRB65 = 0
Clarithromycin
500mg 2 x daily
5 days
If CRB65=1 or 2 & AT HOME - clinically assess need for dual therapy for atypicals:
Amoxicillin
500mg 3 x daily
5 days
AND (if dual therapy for atypicals required)
Clarithromycin
500mg 2 x daily
5 days
Alternative treatment
If CRB65=1 or 2 & AT HOME
Doxycycline alone
(not suitable for those under 12 years)
200mg on Day 1
then 100mg once daily
5 days
Start antibiotics immediately.
Use CRB65 score to assess severity.
Each CRB65 parameter scores 1:
Confusion (AMT≤8); Respiratory rate ≥30/min; BP systolic <90 or diastolic ≤60; Age ≥65;
If no response in 48 hours consider admission.
If CRB 65 = 1 or 2 consider need for hospital admission. If at home, clinically assess need for dual therapy for atypicals.