Acute Infective Exacerbation of COPD

Treat exacerbations promptly with antibiotics if purulent sputum

and increased shortness of breath 

and/or increased sputum volume.

Consider sputum sample for culture and delayed prescription.


500mg 3 x daily

5 days

Penicillin Allergy:


(not suitable for those under 12 years)


200mg on Day 1

then 100mg daily


5 days