Acute upper gastrointestinal haemorrhage in patients with decompensated liver disease

Micro Organisms

Escherichia coli, Gram positive cocci, Enterococci


5 days

  • Collect appropriate specimens for culture before starting treatment
  • Seek specialist advice if appropriate
1st line

If IV route required:

IV Co-trimoxazole* 960mg 12 hourly

Oral switch

Co-trimoxazole 960mg 12 hourly

*If IV Co-trimoxazole unavailable and IV route required use IV ciprofloxacin 400mg 12 hourly. Oral switch remains co-trimoxazole.

2nd line

If IV route required:

Ciprofloxacin 400mg IV 12 hourly

Oral switch

Ciprofloxacin 500mg 12 hourly