Acute Mastoiditis

First Line

Ceftriaxone (at CNS doses) IV + Metronidazole IV/PO for 10-14 days - minimum 5 days IV

Co-amoxiclav PO for oral switch

Anaphylaxis (including severe skin reaction) to penicillin / cephalosporins

Vancomycin IV + gentamicin IV + metronidazole IV/PO

Notes

Involve ENT