Intra-cardiac prosthesis

First Line

Vancomycin IV + gentamicin IV (treatment dose, not synergistic dose) for 4-6 weeks

Discuss with specialist for course length of gentamicin

Consider adding rifampicin once identification and sensitivities are known.

 

Use paediatric gentamicin for dosing guidance and target levels

Target vancomycin level - Trough: 15-20mg/l for pulsed infusion.