Pneumonia In Immunocompromised

First Line

Piperacillin-Tazobactam (Tazocin) 4.5g IV 6 hourly

ADD Clarithromycin 500mg PO/IV 12 hourly if community acquired pneumonia

 

Penicillin Allergy

Levofloxacin 500mg PO 12 hourly (consider safety issues)

(No additional clarithromycin required if community acquired as excellent atypical cover)

 

If already on ciprofloxacin prophylaxis:

Vancomycin IV AND Gentamicin IV as per protocol

Add Clarithromycin 500mg PO/IV 12 hourly if community acquired pneumonia

 

 

Notes

e.g on immunosupressant drugs, neutropenia

Ensure sputum and atypical pneumonia screens sent ASAP

If there is treatment failure/relapse check microbiology results, seek senior clinical review +/- consider discussion with Consultant microbiologist