Gastroenteritis and Colitis
Most infections will be self-limiting in nature.
Even bacterial infections e.g. Campylobacter, Salmonella are commonly self-limiting.
Send stool sample for culture. If bacterial pathogen identified, report will contain comment to guide management.
If C. difficile infection is suspected - review guidance "Clostridium difficile assocaited disease" guidance and consider empirical management.
Antibiotic therapy should be avoided due to increased risk of HUS in potential Shigatoxin-producing E.coli (e.g. 0157) infection and risk of exacerbating potential C. difficile infection
Gentamicin as per protocol
Amoxicillin 1g IV 8 hourly (or Vancomycin IV as per protocol if penicillin allergy)
Metronidazole 400mg PO 8 hourly or 500mg IV 8 hourly
Treatment duration: 5 days
Oral switch guidance
Review culture results first. If no positive microbiology to guide:
Preferred regime - Co-amoxiclav 625mg PO 8 hourly
Alternative - Co-trimoxazole 960mg PO 12 hourly AND Metronidazole 400mg 8 hourly
Review need for antibiotics daily including any available microbiology results.