Gynaecological Sepsis (including post-op)

First Line

Gentamicin IV as per protocol AND Amoxicillin 1g IV 8 hourly AND metronidazole 500mg IV 8 hourly

Penicillin Allergy

Vancomycin IV AND Gentamicin IV as per protocol AND Metronidazole 500mg IV 8 hourly


Incl. abscess /  Foreign device infections

Send blood cultures  and other relevant samples

Check previous / recent microbiology results for guidance




Treatment duration: 7 days (may be longer if complicated source of infection e.g. absess or collection)


Oral switch guidance

Review culture results first. If no positive microbiology to guide:

Preferred regime - Co-amoxiclav 625mg PO 8 hourly

Alternative - Co-trimoxazole 960mg PO 12 hourly AND Metronidazole 400mg PO 8 hourly