Acute Exacerbation of COPD


Acute Exacerbation of COPD


Duration 5 days

First Line

Amoxicillin PO 500mg three times daily

2nd line / allergies / previous antibiotics

Doxycycline PO 200mg on day 1 then 100mg once daily


Give antibiotics if increase in purulent sputum. If no increased sputum purulence then no antibiotics unless consolidation on CXR or signs of pneumonia