Bacterial Meningitis / Encephalitis
Typical duration = up to 10 days.
Cefotaxime 2g IV 6 x daily ( 4 hourly) for the first 24 hours.
Reducing appropriate to clinical response. Seek Consultant Microbiologist / ID Consultant advice on further treatment
Consultant microbiologist MUST contacted before prescribing to approve.
Chloramphenicol 25mg / kg IV 6 hourly
WARNING: Associated with serious haematological side effects. Full blood counts required daily during treatment.
Reduce dose as soon as clinically possible
Amoxicillin 2g IV 6 X daily (4 hourly)
Typical duration = up to 14 days.
If meningococcal or penicillin sensitive pneumococcal isolate confirmed change to :
Benzypenicillin 2.4g IV 4 hourly
Typical duration= 10 – 14 days
Aciclovir 10mg / kg IV 8 hourly
Suspected Herpes simplex virus. Discuss with consultant Microbiologist
Typical duration = 10 - 21 days
NO ANTIBIOTICS NECESSARY
Suspected meningococcal meningitis is a medical emergency and requires urgent resuscitation and antibiotics. Collect blood cultures, CSF if possible ,throat swab and EDTA blood meningococcal PCR but do not delay giving antibiotics.
Meningitis should be reported to the duty Public Health Consultant who will give guidance on the necessity of prophylaxis treatment.