Pelvic Inflammatory Disease (PID)

Duration

14 days (total duration IV plus oral)

Outpatient Therapy for Pelvic Inflammatory Disease (PID)

For mild to moderate PID (no fever, systemically well)

Doxycycline oral 100mg 12 hourly

Plus

Metronidazole oral 400mg 12 hourly

 

If doxycycline contraindicated

Ofloxacin oral 400mg 12 hourly

Plus

Metronidazole oral 400mg 12 hourly

 

For moderate to severe PID or where there is a high risk of gonococcal infection

Ceftriaxone IM 1g single dose followed by:

Doxycycline oral 100mg 12 hourly plus Metronidazole oral 400mg 12 hourly

Inpatient Therapy for moderate to severe PID

First line if able to tolerate oral medication

Ceftriaxone IV 2g daily

Plus

Doxycycline oral 100mg 12 hourly

Plus

Metronidazole oral 400mg 12 hourly

 

Review ceftriaxone daily and STOP 24 hours after clinical improvement - single dose treatment acceptable

 

Second line treatment (severe penicillin allergy or oral route not available)

Ofloxacin IV 400mg 12 hourly

plus

Metronidazole IV  500mg 8 hourly

IV to oral switch: oral ofloxacin 400 mg 12 hourly + Metronidazole 400mg 12 hourly

Notes

See NHS Borders Sexual Health STI protocols for more details