Protected Antibacterial and Antiviral agents

Use of the following antibacterials and antivirals by non-specialists is only permitted for the listed indications.

Use outwith the listed indications must be on recommendation of a Microbiology/Infectious Disease specialist.

All use is subject to licensing and SMC restrictions where these are in place.

 

Drug

Permitted indications for non-specialist use

Amikacin

 N.A.

Aztreonam

 N.A.

Cefazolin

 N.A

Ceftazidime

Empirical treatment of CAPD peritonitis

Exacerbation of COPD/bronchiectasis in patients colonised with P. aeruginosa or resistant gram negative organisms.

Ceftazidime/avibactam (Zavicefta)

 N.A.

Ceftolozane/tazobactam (Zerbaxa)

 N.A.

Ceftriaxone

Proven or suspected bacterial CNS infection

Pelvic inflammatory Disease/tubo-ovarian abscess

Uncomplicated gonorrhoea.

Cefuroxime

Surgical prophylaxis as per NHS Ayrshire and Arran guidelines.

Chloramphenicol (IV only)

Suspected meningitis in penicillin anaphylaxis.

Ciprofloxacin (IV only)

Neutropenic Sepsis in patients with anaphylaxis to penicillins

Indications in line with Empirical Antimicrobial Policy, but oral route compromised.

Clindamycin

Diabetic foot infection on advice from Consultant Diabetologist

Pelvic-inflammatory disease and tubo-ovarian abscess in patients with anaphylaxis to penicillins.

Suspected chorioamnionitis with Group B strep (GBS) prophylaxis in patients with anaphylaxis to penicillins.

Colistin

 N.A.

Co-trimoxazole

Suspected or proven Pneumocystis jiroveci pneumonia, including prophylactic use.

Dalbavancin

 N.A.

Daptomycin

 N.A.

Ertapenem

 N.A.

Fidaxomicin

 N.A.

Foscarnet

 N.A.

Fosfomycin (IV only)

 N.A.

Imipenem (+ cilastatin)

 N.A.

Linezolid

 N.A.

Meropenem OR

Meropenem-vaborbactam

 N.A.

Piperacillin/tazobactam

First line treatment of febrile neutropenia in line with policy

Pentamidine

 N.A.

Tedizolid

 N.A.

Teicoplanin

For surgical prophylaxis as per NHS Ayrshire & Arran guideline

Temocillin

Empirical treatment of Spontaneous bacterial peritonitis (SBP)

Ticarcillin/clavulanate

 N.A.

Tigecycline

 N.A.

Tobramycin

 N.A.