Uncomplicated Lower UTI in Pregnancy
If positive urine cultures are available, therapy choices should be based on the released sensitivities.
Trimethoprim is contraindicated in the 1st trimester of pregnancy.
Nitrofurantoin 50mg PO every 6 hours (avoid if eGFR < 45ml/min)
Or Cefalexin 500mg PO every 8 hours
Nitrofurantoin is contraindicated in the 3rd trimester of pregnancy.
Cefalexin 500mg PO 8 hourly
Or Trimethoprim 200mg PO 12 hourly
Trimethoprim is unlicensed for this indication.